Strategies for mitigating an influenza pandemic
نویسندگان
چکیده
منابع مشابه
Strategies for mitigating an influenza pandemic with pre-pandemic H5N1 vaccines.
The recent worldwide spread of the swine-origin H1N1 2009 influenza outbreak has resulted in its designation as a pandemic by the World Health Organization. While it appears to result in mild symptoms, concern still exists that a more severe influenza pandemic with a high case fatality ratio might arise by reassortment or mutation of the currently circulating avian influenza (H5N1) virus. Given...
متن کاملVaccination strategies for an influenza pandemic.
An influenza pandemic represents one of the greatest acute infectious threats to health. The 1918–1919 influenza pandemic caused an estimated 500,000 deaths in the United States, making it the most fatal event in all of US history. The spread of highly pathogenic avian H5N1 influenza across much of Asia creates a substantial risk of igniting the next pandemic. In 2004, 44 human cases caused by ...
متن کاملDiagnosis and Antiviral Intervention Strategies for Mitigating an Influenza Epidemic
BACKGROUND Many countries have amassed antiviral stockpiles for pandemic preparedness. Despite extensive trial data and modelling studies, it remains unclear how to make optimal use of antiviral stockpiles within the constraints of healthcare infrastructure. Modelling studies informed recommendations for liberal antiviral distribution in the pandemic phase, primarily to prevent infection, but f...
متن کاملCost-Effective Strategies for Mitigating a Future Influenza Pandemic with H1N1 2009 Characteristics
BACKGROUND We performed an analysis of the cost-effectiveness of pandemic intervention strategies using a detailed, individual-based simulation model of a community in Australia together with health outcome data of infected individuals gathered during 2009-2010. The aim was to examine the cost-effectiveness of a range of interventions to determine the most cost-effective strategies suitable for...
متن کاملStrategies for containing a global influenza pandemic.
Mathematical modelling provides useful insight into the geographic and temporal spread of pandemic influenza. It has been recently used to assess the ability to stop a pandemic at a very early stage. Here, we model the global diffusion of pandemic influenza and the impact of available preventive and control measures. We refined a published SEIR deterministic model of disease dynamics within 52 ...
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ژورنال
عنوان ژورنال: Nature
سال: 2006
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature04795